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The peril associated with any pharmacologic intervention in cirrhotic patients is considerable, given the propensity of NSAIDs to exacerbate ascites, renal impairment, and gastrointestinal hemorrhage

This observed beneficial effect could be mediated through a reduction in body mass index (BMI), leptin concentration and body fat percentage (43)

(5) Berger DR, Centeno CJ, Steinmetz NJ