i'm on a glp-1 microdosing is popular, but there's little evidence it works I'm stuck in the gray

It can be easier to source but harder to document

The association was still present when patients on medications for opioid, alcohol, or nicotine use disorder were excluded, with a 44% lower risk during active GLP-1 use and a 28% lower risk after discontinuation

(Or just survive walking down the stairs after leg day!) 4

2020;10:e01726

Its primary actions include: Inhibiting the reuptake of dopamine and noradrenaline in the central nervous system Minimal effect on serotonin pathways, distinguishing it from most other antidepressants Potential appetite suppression as a secondary effect, though this is not its primary indication Reducing nicotine cravings through dopaminergic pathways Bupropion is metabolised primarily in the liver by the CYP2B6 enzyme system, producing active metabolites

They can be combined together