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This state is characterized by increased collagen I and -SMA expression, as well as disruption of the MMP/TIMP balance, culminating in pathological ECM accumulation

Effect of L-carnitine and propionyl-L-carnitine on endothelial function of small mesenteric arteries from SHR

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doi: 10.1124/jpet.116.235069

However, the related mechanism of blood oxygen content and serum ions in a hypoxic environment must be studied further