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IGF signaling pathway in granulosa cells during human ovarian follicle development Despite numerous differences in the reproductive systems of men and women, the behavior versus gonadotropins, such as the synthesis and secretion of sex steroids and cell proliferation, is highly similar in both systems

Rectal tumour biopsies ( n =10) were collected from consenting patients undergoing diagnostic endoscopy, a baseline measurement of metabolic rate was recorded, biopsies were treated for 24 h with metformin (10 mM) or H 2 O vehicle control and metabolism was assessed at 24 h post treatment

metabolites, primarily mediated through the Nrf2 pathway, is highly relevant (Yuan et al., 2020)

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Makowska-WierzbickaDMichalakSKarczewskiJDobrowolskaAWierzbickaAStelmach-MardasM

10.1016/j.psj.2022.101725 46 LiX.YaoY.WangY.HuaL.WuM.ChenF.et al (2022)