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[11] GABA A receptors are ligand-activated chloride channels: when activated by GABA, they allow the flow of chloride ions across the membrane of the cell

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Effects of NAC administration in HCCAA patients The L68Q-hCC mutation is a founder mutation in the Icelandic population that occurred approximately 18 generations ago during the 16th century 4 , with most mutation carriers suffering microinfarcts and brain hemorrhages as young adults, ultimately leading to paralysis, dementia, and death

Markowitz et al, 1988

[PMC free article: PMC4994058] [PubMed: 27602020] 196