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Tang et al., 2020

This study followed a two-group, randomized controlled trial design

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Around S = 1.4, the GS flux starts to increase more slowly while the GPX flux still increases at roughly the same rate as S increases, so the GSH curve starts to level off and reaches a maximum at S = 1.8

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Overall, these results suggest that SARS-CoV-2 strongly relies on a profound induction of metabolic pathways for its replication and support the notion that the cellular metabolism of virally infected cells is an attractive target for inhibiting viral replication