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The enteric nervous system relays psychological stress to intestinal inflammation

Curr Neuropharmacol 2021;19:120224

An oral 2-hydroxypropyl--cyclodextrin-loaded spirooxindole-pyrrolizidine derivative restores p53 activity via targeting MDM2 and JNK1/2 in hepatocellular carcinoma

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Oxidative stress and chronic inflammation are also considered to be the key factors that lead to the slow healing of wounds in diabetes

Although this might be explained by the stochastic acquisition of multiple amplifications, we wondered whether such ploidy change more likely resulted from whole-genome doubling (WGD) events that occurred against a background of smaller-scale stochastic amplifications and deletions