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The approval of Wegovy represents a turning point for healthcare providers to embrace medical management of obesity to help improve chronic weight management for patients. For more than two decades, Novo Nordisk has led the charge to translate the complex science behind obesity into medicines that can make a difference, all while partnering across industries and sectors to change how obesity is understood, diagnosed and treated, said Doug Langa, executive vice president, North America operations and president of Novo Nordisk Inc

PMID: 37095171, PMCID: PMC10125992, DOI: 10.1038/s41598-023-33683-1

Samples were collected soon after birth, prior to the development of symptoms, and later at diagnosis

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Moreover, acrolein itself can inactivate ALDH2 activity by forming adduct at its NAD binding site [32]