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doi: 10.1152/ajpendo.00346.2015 58 SimpsonKParkerJPlumerJBloomS

Approximately equal numbers of patients were randomized to receive placebo, 100 mg of sitagliptin once daily, 500 mg or 1000 mg of metformin HCl twice daily, or 50 mg of sitagliptin twice daily in combination with 500 mg or 1000 mg of metformin HCl twice daily

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The effects of UA in fructose metabolism and potential deleterious metabolic effects have been earlier discussed (,)

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