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doi: 10.1210/jc.2012-3888 119 GoldstoneAPHollandAJHauffaBPHokken-KoelegaACTauberM

IV administration also introduces risks that oral supplementation does not: Contamination or excessive endotoxin exposure Sterility and compounding failures Infusion reactions Venous irritation or infection Dosing errors Additional cost and clinical complexity The FDA has reported adverse events among patients who received injectable compounded glutathione made with an unsuitable dietary ingredient

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Some studies suggest AOD-9604 may support collagen synthesis in chondrocytes and reduce joint inflammation, which could be a secondary benefit for anyone carrying excess weight that stresses their joints

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