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Joung JK, Sander JD

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A Phase 2 trial (NCT01311518) was designed to test RGN-352 in ~75 heart attack patients, but was placed on FDA clinical hold in 2011 due to manufacturing (GMP) compliance issues at the contract site not safety concerns with the drug itself

Description Research Overview 5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule research compound studied for its observed inhibitory activity against nicotinamide N-methyltransferase (NNMT)

Wainwright P, Narayanan S, Cook P Clinical biochemistry 2015