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17,18 In a post-hoc analysis of the SUSTAIN-6 study, the additional risk factors of speed of hemoglobin A1c reduction with treatment, poor baseline glycemic control and insulin use at the initiation of GLP-1/GIP agonist treatment were reported ( Table 2 )

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doi: 10.3389/fimmu.2023.1163288 Received 10 February 2023 Accepted 30 October 2023 Published 20 November 2023 Volume 14 - 2023 Edited by Zebin Weng, Nanjing University of Chinese Medicine, China Reviewed by Jose Francisco Kerr Saraiva, Pontifical Catholic University of Campinas, Brazil