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It has been reported that antibodies to SOD are potentially responsible for increased oxidative damage in SLE patients

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Inhibiting glutamine pathway, including downregulating glutamine transporter ASCT2 [84] or inhibit glutaminase by CB-839 [85] can deplete intracellular GSH, but such effect of CB-839 was only observed in cancer cell lines expressing xCT supplied with high cystine in the culture [86]

Some individuals experience mild gastrointestinal effects including nausea or abdominal discomfort, particularly with higher doses or when first initiating therapy

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The capsule format offers a simple, travel-friendly option for daily supplementation without the need for refrigeration