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Maintaining energy homeostasis requires substrate sensing, trafficking storage and utilization, dependent on substrate availability and energy requirement [4,18]

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Glutathione acts to protect the mitochondria of cells by eliminating free radicals [5]

Function enrichment KEGG enrichment, GO enrichment, and GSEA analysis were implemented in the clusterProfiler R package (v4.7.1.2)

Topical niacinamide stabilizes the epidermal barrier function with increased protein and ceramide synthesis and keratinocyte differentiation, improving skin microrelief and attenuating fine wrinkles

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