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Description

Scheme 23

Dis ., 25 (4), 370375

Side effects are similar to those seen with other GLP-1 receptor agonists and tend to decrease over time

The result is a more comprehensive metabolic response that affects appetite, fat storage, insulin sensitivity, and energy expenditure simultaneously

Birth of the incretin concept The same year Lim and Kosaka published their hypothesis, the Belgian physiologist La Barre attempted to purify secretin with Eugene Still, a colleague at the University of Chicago