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Patients who are informed about potential side effects or who read about others' experiences may be more likely to notice and report mild systemic symptoms that might otherwise go unrecognized

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Use objective thresholds to guide decisions, for example, a persistent weekly weight drift of 0.5 to 1 percent or fasting glucose excursions beyond agreed-upon targets, as triggers for clinical reassessment

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We applied glucose tolerance tests after an additional 13 weeks of semaglutide intervention