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Clinical Data on Tesofensine for Weight Loss Tesofensines weight loss potential was first demonstrated in a landmark 24-week randomized, double-blind, placebo-controlled trial published in The Lancet a study that quickly set it apart from other anti-obesity compounds

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In recent years, the establishment of cross-tissue single-cell atlases has systematically revealed the lineage and functional heterogeneity of human monocytes/macrophages in health and disease, providing an important reference framework for analyzing metabolism-phenotype coupling at the human level (135)

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This work was supported by the grants from Jiangsu Provincial Research Hospital (YJXYY202204-YSB38 and YJXYY202204-2-YSC12), and the Project of Jiangsu Degree and Graduated Students Education Association (JSYXHXM2023-ZYB19)

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