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When deficient, it can increase the accumulation of homocysteine, which is significant in the development of cerebrovascular diseases and cognitive impairment (4, 20, 58)

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10.1016/j.expneurol.2006.10.013 27 CaoY.YangL.QiaoX.XueC.XuJ

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Due to the distinct position of the conjugated N-terminal lipid between Cagri-CTR and Cagri-AMY 1 R, we also determined a structure of CTR-Gs in complex with an analogue of Cagri that lacked the lipid modification (CagriBB) to interrogate the contribution of the acylation to the conformation of Cagri-CTR complex

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