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Absolute contraindications include personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), previous serious hypersensitivity to semaglutide or formulation components, pregnancy (the medication should be discontinued at least 2 months before planned conception), and breastfeeding due to insufficient data on excretion in human milk

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It plays a vital role in: Energy production Cellular repair Cognitive function Metabolic efficiency As we age, NAD+ levels naturally decline, which can impact energy, focus, and overall vitality

doi: 10.1093/gerona/gls070

doi: 10.1210/jc.2013-3059