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282 Pertaining to microglia/macrophages, lactate and histone lactylation promote the conversion of macrophages to M2-type tumor-associated macrophages (TAM), while TAM enhances the transcription of M2-like genes hypoxia-inducible factor 2 (HIF-2), ARG1, and VEGF

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Low-grade endotoxemia, diet, and gut microbiotaan emphasis on the early events leading to dysfunction of the intestinal epithelial barrier

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