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further research is warranted to understand the mechanisms underlying these differences [81]

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E., Specht E., Broedbaek K., et al., RNA Modifications by Oxidation: A Novel Disease Mechanism?, Free Radical Biology and Medicine 52 (2012): 13531361, 10.1016/j.freeradbiomed.2012.01.009

Nearly all of KMT2A rearrangements are classified as translocation mutations, which produce a fusion protein that binds to the menin protein, triggering the development of leukemia

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