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Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

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doi: 10.1002/jps.2600590215

Feeling hot or cold Unusual hunger and weight gain Dry mouth Fatigue and dizziness Heart problems such as abnormal rhythms Blood pressure changes (increase or decrease) Anecdotal side effects Anxiety and loss of sleep (Taking in AM and early afternoon helped (having doses around 250-350mg))

It is a modified analog of glucagon-like peptide-1 (GLP-1), involved in glucose signaling and metabolic regulation