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Lower LDL Cholesterol: In a two-year study in 65 elderly volunteers, the daily administration of MK-677 at the dose of 25mg was found to markedly reduce low-density lipoprotein (LDL) cholesterolor bad cholesterol. While the placebo group had a 0.12mmol/l increase in LDL, the MK-677 group saw a decrease of 0.14mmol/l within the first year of the study [19]

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