The third is duration and safety : short controlled studies in animals say almost nothing about what months or years of exposure would do in a human, which is precisely why the cycling section defaults to scheduled off periods rather than open-ended use
These observations were further validated by 3D large-area multiphoton/confocal hybrid imaging (Nikon AXR MP/Confocal), which confirmed increased collagen deposition within adventitial interstitium where Mgks accumulate in TSP1 PF4 KO reporter mice lungs (Fig
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