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In Orai1 knockout mice, the LPS-induced depression-like behavior, including the helplessness and pleasure deficit, is improved in astrocytes (Novakovic et al., 2023)
They are distinct but highly synergistic in bioenergetic research models
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Prioritizing protein (1.2-1.6g per kg body weight), fiber-rich vegetables, and adequate hydration supports any weight management protocol regardless of which specific medication you use
When reserves are adequate, cells can function at optimal parameters