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Notably, GLP-1-producing neurons within the nucleus tractus solitarius (NTS) project axons to the VTA and other limbic structures, further embedding GLP-1 signaling within neural networks that regulate reward and motivation (Llewellyn-Smith et al., 2011

This could lead to reduced demand for snacks, sweets, sugary beverages, and other foods commonly associated with indulgence and comfort eating. Shift in Consumer Preferences As users of GLP-1 medications experience less hunger and eat smaller portions, they may shift towards more nutrient-dense foods that offer better satiety per calorie, like protein-rich foods, fruits, and vegetables

McDonalds is busy with shoppers, while chains from Subway to German Doner Kebab are opening their doors for the approaching army of hungry stomachs

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Currently available FDA-approved GLP-1 RAs include several monotherapy agents and one combination multi-agonist, the dual GLP-1/GIP agonist tirzepatide (Zheng et al., 2024)

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