A: Evening dosing can worsen reflux symptoms in susceptible individuals because delayed gastric emptying increases the likelihood of reflux when lying supine
DSIP enhances mitochondrial oxidative phosphorylation in the brain, which helps maintain brain function during periods of low oxygen (hypoxia)
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severe or persistent upper abdominal pain should prompt urgent medical assessment [10] [11] Dehydration and acute kidney injury (AKI): gastrointestinal fluid losses can lead to dehydration, which may precipitate AKI, particularly in those with pre-existing renal impairment or those taking nephrotoxic medicines Delayed gastric emptying: this may affect the absorption of orally administered medicines, including contraceptive pills and thyroid replacement therapy [11] Injection site reactions: redness, bruising, or discomfort at the subcutaneous injection site Heart rate changes: increases in resting heart rate have been noted with GLP-1 class agents [14] [15] Hypoglycaemia: particularly if used alongside insulin or sulphonylureas Potential pancreatitis risk: a class concern with GLP-1 receptor agonists
Practical tip : Add a small serving of fermented foods to one meal daily
