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We found that skin lesions of IMQ- treated mice displayed a gene expression pattern that mimicked downregulation of GPX4 and upregulation of ACSL4 and 4-HNE-modified protein levels in erastin-treated keratinocytes (Fig

Animals were housed in standard cages with sawdust bedding and maintained under controlled environmental conditions (22 1 C), with a 14-h light/10-h dark cycle