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Description

The MHRA advises that insulin doses should not be reduced rapidly when initiating a GLP-1 receptor agonist, as this may increase the risk of diabetic ketoacidosis (DKA)

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6,8 Studies looking at higher doses, such as one comparing 12.5mg, 25mg, and 50mg, found a non-dose-dependent steady-state level maximum at the 25mg dose

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