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Once that mechanism runs its course, or once the patient is off the medication, the underlying adipocyte metabolism is largely unchanged

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It's not really changing the course of the disease

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According to studies, MT-II increases pigmentation at a lower cumulative dose than MT-I but has been associated with increased side effects, namely as regards satiety and sexual behavor [4]

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wherein R is H, alkyl, cycloalkyl, or arylalkyl

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This is not evidenced based medicine, theyre experimenting with patients

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Now these are theories and I'm putting 'em out there

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