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The prepared topical formulation exhibited prolonged drug release patterns ( 6.4 Transfersomes Transfersomes are biocompatible vesicular nanocarriers with high deformability potential that are composed of lipids bilayer and membrane softeners (Hatem et al., 2018)

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High levels of -tocopherol in plasma have also been related to high-grade prostate cancer [54]

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The authors hypothesized that H 2 O 2 formation in the mitochondria results in the inactivation of ATG4, promoting ATG8 lipidation, and thus, activation of autophagy