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Real-time quantitative PCR Real-time PCR was performed to quantify specific mRNA

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On the other hand, in another study of PSD, a high dose of caffeine impairs memory and leads to an anxiogenic and depressive-like behavior in the hole board and elevated plus maze tests, and social interaction and locomotor activity, respectively, also increased pro-inflammatory cytokines such as TNF-alpha and IL-6 [37]

Homma, T., Kobayashi, S., Sato, H

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Faverzani JL, Hammerschmidt TG, Sitta A, Deon M, Wajner M, Vargas CR (2017) Oxidative stress in homocystinuria due to cystathionine -synthase deficiency: findings in patients and in animal models