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The model could be relevant to address limitations of conventional animal models and could prove useful to detect undesirable drug adverse events to avoid unnecessary animal suffering during preclinical testing

This is an area of active research

Naltrexone and low dose naltrexone have both also been shown to reduce inflammation in the body

Insulin is the hormone that helps move sugar from the bloodstream into cells

Antioxidant insufficiency promotes oxidative damage

Tesofensine, a novel triple monoamine reuptake inhibitor, induces appetite suppression by indirect stimulation of 1 adrenoceptor and dopamine D1 receptor pathways in the central nervous system