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The authors mentioned that intranasal administration facilitated brain-targeted delivery (DTE % = 314.29%) owing to the nanoscale size and lipid nature of liposomes, which facilitated the transcellular transport of drug molecules via various endocytic pathways in sustentacular and neuronal cells within the olfactory membrane
10.1007/s10856-018-6123-8 127 MahmoudA
Limiti dei dati di sicurezza: La principale limitazione riguarda la mancanza di dati di sicurezza a lungo termine nell'uomo
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Most remarkably, ARA-290 initiated measurable regrowth of small nerve fibers in the cornea, providing direct evidence of nerve regeneration in humans
Horike, S., Cai, S., Miyano, M., Cheng, J
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