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Compared to placebo, GLP-1 receptor agonists reduced the risk of kidney failure by 16% and the worsening of kidney function by 22% (defined by a drop in estimated glomerular filtration ratea measure of how much blood the kidneys filter clean every minuteof at least 50%)

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These agents have transformed the therapeutic landscape, supported by large outcome trials demonstrating significant reductions in major adverse cardiovascular events in high-risk patients with type 2 diabetes [1, 2]

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