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26 for the federal government to cover the medications to treat obesity or Medicaid patients nationwide, in addition to Medicare patients

The maximum target maintenance dose is 2.4 mg weekly for weight management

The active ingredient in Wegovy is semaglutide, and dulaglutide in Trulicity

The extra water in the stool makes it easier to pass

In large obesity trials, incident high blood pressure occurred in fewer than 1% of semaglutide users versus about 2% on placebo, suggesting no clear causal link

The data is consistent across trials: tirzepatide 15mg produces ~6 percentage points more weight loss than semaglutide 2.4mg, and even tirzepatide's lowest dose (5mg) matches semaglutide's maximum