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In this context, PH20, I-BET151, and PXS-5153A may indirectly counteract thyroid-related fibrosis by degrading ECM, inhibiting profibrotic signaling, or reducing collagen crosslinking

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Ca 2+ -driven cell death of erythrocytes can occur even without activation of caspases

The latter effect is the result of the reduced ability for platelets to adhere to exposed sub-endothelial extracellular matrix collagen which is required for their activation

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The brain as a source and a target of prolactin in mammals