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CNS : stimulation of central presynaptic 2 receptors causes a decrease in release of norepinephrine and dopamine resulting in

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Schwartz R, Kliper E, Stern N, Dotan G, Berliner S, Kesler A

Epilepsy Behav 104:106897

Individual patient factorsincluding the reason for cholecystectomy, time since surgery, and presence of ongoing digestive symptomsshould inform treatment decisions

Interestingly, astrocyte reactivity is influenced and modulated by microglia activation, suggesting that drugs targeting microglia may offer an indirect strategy to combat reactive astrocytes