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Both drug classes affect appetite signaling and cardiovascular hemodynamics, requiring careful provider assessment before initiation

Much of the available safety information comes from animal studies, provider observations, and user-reported experiences

doi: 10.1016/j.jhep.2020.02.027 177 RatziuVSanyalAHarrisonSAWongVWFrancqueSGoodmanZet al

It works through the bodys natural GH axis

Moreover, rare but notable mood changes including reports of increased anxiety or agitation have been documented in anecdotal and observational studies, suggesting clinicians should closely monitor emotional well-being during initial titration periods

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