The findings indicate that HFpEF is associated with various comorbidities, such as obesity, diabetes mellitus, and hypertension, which contribute to endothelial dysfunction
STING is transported by clathrin-coated vesicles and recycling endosomes (141) and directly encapsulated in lysosomal associated membrane protein 1 (LAMP-1) positive compartments through the ESCRT components tumor susceptibility gene 101 (TSG101) and vacuolar sorting-associated protein 4 (VPS4) (165)
Personalized approaches are critical, as host genetics, diet, and baseline microbiota composition significantly influence outcomes (203, 204)
Do GLP-1-based therapies increase cancer risk
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
31 P-MRS study of acetyl- L -carnitine treatment in geriatric depression: preliminary results