For instance, in a pooled analysis of clinical trials, patients treated with semaglutide showed a slightly higher rate of gallbladder disorders compared to those on placebo or other diabetes medications
It also improves insulin sensitivity, which can benefit individuals with type 2 diabetes
It works by mimicking a naturally occurring hormone, GLP-1, which is released by the gut after we eat and makes us feel full
The semaglutide shortage context Compounded semaglutide became widely available during the semaglutide drug shortage that lasted from early 2022 through February 2025
One challenge to the whole GLP-1 landscape is access to them in the first place, between shortages, high costs, and lack of insurance coverage
Significant weight loss from GLP-1 therapy may reduce levothyroxine requirements in some patients