The primary effects don't overlap much, so you're getting additive benefit rather than redundancy
Cell Mol Life Sci 75(12):21772195 Boffa G, Signori A, Massacesi L, Mariottini A, Sbragia E, Cottone S, Amato MP, Gasperini C, Moiola L, Meletti S, Repice AM, Brescia Morra V, Salemi G, Patti F, Filippi M, De Luca G, Lus G, Zaffaroni M, Sola P, Conte A, Nistri R, Aguglia U, Granella F, Galgani S, Caniatti LM, Lugaresi A, Romano S, Iaffaldano P, Cocco E, Saccardi R, Angelucci E, Trojano M, Mancardi GL, Sormani MP, Inglese M, Italian BMTMSSG, M
Across GLP-1 trials, about 60% of lost weight returns within the first year and roughly 75% returns over the longer curve, with the fastest regain in the early months. In semaglutides extension, about two-thirds returned within one year. The pattern reflects removal of appetite suppression after major weight loss
(Springer International Publishing), 343377
Glutathione and Autoimmunity: A Lifesaver Autoimmune diseases occur when the immune system mistakenly attacks the body's tissues, leading to inflammation, pain, and organ damage
Some compounded tirzepatide formulations even include B12but these are not FDA-regulated and carry potential risks
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