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In rat and human tissue, high signals for GHSR1a mRNA are found expressed in several hypothalamic nuclei, the pituitary, and the dentate gyrus of the hippocampus, with additional yet reduced signals in CA2 and CA3 of the hippocampus, the substantia nigra, the ventral tegmental area, and the median raphe nuclei (Guan et al., 1997

Its reduced IGFBP binding means that a greater proportion of the peptide remains free to interact with the IGF-1 receptor (IGF-1R), making it a more potent and predictable tool for in vitro research

For a 190-pound person, that translates to 133 to 190 grams of protein per day

Phase I clinical trial in healthy volunteers to study safety and pharmacokinetics of BPC-157, a pentadecapeptide from gastric source

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