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Exclusion criteria were as follows: type 1 diabetes or positivity for anti-glutamic acid decarboxylase autoantibodies, secondary forms of diabetes, acute metabolic complications, liver disease, renal dysfunction or patients under anticoagulant treatment, previous bariatric surgery, congenital or acquired abnormalities of the digestive tract, pregnancy, nursing or desired pregnancy in the 12 months following inclusion, and corticoid use by oral or intravenous route for more than 14 consecutive days in the last 3 months
10.1161/CIRCIMAGING.117.007372 94
Diagnosis depends on the total body surface area involvement of detached/detachable skin lesions: 30% represent SJS, SJSTEN overlap, and TEN, respectively
Compromised liver function can alter the safety and efficacy of both interventions
Non-targeted analyses UHPLC-ESI-QTOFMS analyses Urine samples and medium samples from the in vitro liver models and the enteric bacteria were analyzed using HRMS-based non-targeted methods as described in David et al
Austin, J
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