Permanent damage is unlikely unless you have overdosed, chronic use with liver compromise, or severe malnutrition
How they work: They slow gastric emptying, which can increase fullness after meals
While most patients return to their baseline state, individual responses vary, and some may experience more pronounced hunger or cravings during the adjustment period
Effects on classic cardiovascular risk factors CVOTs on GLP-1RAs Data from the major CVOTs ELIXA, SUSTAIN-6, EXSCEL, HARMONY, PIONEER 6, LEADER, REWIND, and AMPLITUDE-O [53, 54, 56, 59,60,61,62,63] support the overall safety of GLP-1RAs relative to major cardiovascular outcomes
The mechanism is attentional: mindfulness practices reduce the automatic triggering of reward anticipation by food cues, and increase the gap between cue and response
M.BleichS