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Description

Intracellular unesterified fatty acids must first undergo thio-esterification to coenzyme A, a process catalysed by acyl-CoA synthases and consuming the equivalent of two ATP, with formation of acyl-CoAs, i.e., to activate fatty acids

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Both are synthesised by the body and available through diet, with supplementation increasingly used for cardiovascular health, mitochondrial disorders, and male fertility

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