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Phase II human trials of thymosin beta-4 (TB-500's parent molecule) have been conducted examining tissue repair rates, with studies reporting acceleration of repair in patients with pressure ulcers, stasis ulcers, and epidermolysis bullosa wounds, though detailed results remain limited in peer-reviewed literature

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Gastroenterology 132, 21312157, doi: 10.1053/j.gastro.2007.03.054 (2007)

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Going aggressive on inflamed skin does not accelerate clearing: it adds trauma to tissue that is already stressed and increases the risk of scarring and pigment damage