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This is because deactivation of NMDA receptors on GABAergic interneurons removes the inhibition of major excitatory pathways that innervate primary neurons of cerebrocortical and limbic brain regions (Olney and Farber, 1995

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10.1038/s41401-021-00650-3 475 WangH.LiuX.YangH.JingX.WangW.LiuX.et al (2023e)

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