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If anything other than sterile saline was added, it may have been a preservative that you had reacted to

Mood and gut feelings

Michael Lin says in the article that arbutin is more gentle and less irritating as its released slowly

This is illustrated in Fig

Packed with powerful actives like Glutathione, Alpha Arbutin, Niacinamide, Vitamin C, and Licorice Root Extract, it works to reduce pigmentation, boost hydration, and improve skin tone

If you hope to keep hyperpigmentation, spots, and lines at bay as well as stave off oxidative stress, aka the root cause of accelerated aging its time to get Glutathione on your radar and into your routine