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Xu F, Armstrong R, Urrego D, Qazzaz M, Pehar M, Armstrong JN, Shutt T, Syed N

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Les personnes de plus de 65 ans prsentent une prvalence de carence de 15 % due une hypoabsorption cause par une atrophie gastrique

NTS (240) were transferred to U-bottom 96 well assay plates containing 200 l of M199 medium supplemented with 5.5 mM D-glucose, penicillin-streptomycin and 5% heat inactivated fetal bovine serum and incubated at 37 C in a 5% CO 2 incubator overnight

Inhibition of the Xc- transport system by genetic (siRNA, CRISPR) or pharmacological means (Erastin, Sulfasalazine) impairs cystine transport and GSH synthesis, leading to the inactivation of GPX4 and induction of ferroptosis [14]